This document describes the strategic directions that will guide CIAT’s work in the coming years. They have been drawn up at a time when both the Center and the international agricultural research system supported by the Consultative Group on International Agricultural Research (CGIAR) are going through profound change. These strategic directions are intended to provide a compelling framework for program development on the basis of CIAT’s strengths and experience, while allowing sufficient flexibility to shape the Center’s future in accordance with the evolution of the CGIAR.