Bacterial septicaemia is a major problem in frog farming in South East Asia. This project aimed to find out how this disease could be controlled. The study concluded that frog phagocytes are very susceptible to bacterial colonization and that stressed frogs are very susceptible to disease. It is necessary to determine how much of a contribution bacterial loads play in pathogen infection, and how to reduce these loads, before specific work is carried out to identify virulent pathogens and prepare protective vaccines. The future of frog farming depends on producing stock with a better standard of general health and in particular, a lower systemic bacterial load.