Nanotechnology is revolutionizing the way we approach food safety, crop protection, and agricultural sustainability. As global challenges such as food security, environmental stresses, and agricultural efficiency demand innovative solutions, nano-enabled technologies have emerged as powerful tools to address these pressing issues. This joint special issue, “Emerging Nano-Enabled Technologies for Sustainable Food and Agriculture”, being published across Journal of Agricultural and Food Chemistry, ACS Agricultural Science & Technology, and ACS Food Science & Technology, aims to highlight nanotechnology’s latest advancements and applications in sustainable food and agriculture, fostering interdisciplinary collaboration and accelerating the adoption of these cutting-edge innovations. The contributions in this issue span a diverse range of applications, highlighting how nanotechnology is redefining the agricultural and food sciences.